24-Hour Emergency Room in Frisco, TX
SignatureCare Emergency Center Frisco, TX
24-Hour Emergency Room in Frisco, TX 75035
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Your Care is our Signature
Get Direction Address: 16300 State Hwy 121, Frisco, TX, 75035
/ Tel: 469-956-4326

Our staff at SignatureCare Emergency Center in Frisco, TX, is here for you 24/7/365. We take pride in providing top-quality emergency care to residents and businesses in Frisco, TX. If you need emergency medical care any time, day or night, please come in. We accept walk-ins; no appointment is needed.
Frisco's Premier 24/7 Emergency Room: Expert Care for Your Family, Without the Wait
When a medical emergency strikes, every second is critical. You need immediate answers, expert care, and a reassuring environment for your family. Choose the award-winning emergency room in Frisco, TX, that is built to prioritize your and your family’s health and peace of mind.
Open 24 hours a day, 365 days a year, our state-of-the-art facility is always ready to provide the high-quality, compassionate emergency care you deserve, precisely when you need it most.
The SignatureCare Difference: Why Frisco, TX Families Trust Us
See a Doctor in 10 Minutes or Less
In an emergency, waiting is not an option. We've eliminated the long waits and crowded waiting rooms typical of other ERs. Our commitment is to have you in a private room and speaking with a physician in 10 minutes or less. Your health is too important to put on hold.

Board-Certified Physicians On-Site 24/7 - You Can Count on Our Expertise
Your care will be provided by board-certified emergency room physicians, true specialists who have completed extensive training and passed rigorous exams to master the complexities of emergency medicine. This distinction, combined with our numerous awards for excellence in care, ensures you and your family are in the most capable hands.
A Welcoming Environment for Everyone
We understand that an ER can be intimidating, especially for children. Our facility is designed to be family-friendly, creating a comfortable and reassuring atmosphere for everyone, from infants (pediatrics) to seniors. For our youngest patients, we offer pediatric-focused amenities like TVs, snacks, and stickers to help ease their anxiety. We also provide warm blankets if you feel cold.
Advanced On-Site Diagnostics for Fast Results
Getting an accurate diagnosis quickly is the first step toward effective treatment. Our Frisco, TX emergency center is equipped with hospital-level diagnostic technology, including multi-slice CT scanners, digital X-rays, ultrasounds, and a fully COLA-certified laboratory. This allows us to get fast, precise answers and begin your treatment without delay.
We provide Comprehensive Emergency Medical Services
We provide immediate, expert medical care for a wide variety of acute illnesses and injuries. Our services include, but are not limited to:
- Cardiac Emergencies: Chest pain, heart attack symptoms, palpitations, and abnormal heart rhythms.
- Respiratory Issues: Asthma attacks, pneumonia, bronchitis, difficulty breathing, and COPD complications.
- Abdominal Pain: Appendicitis, gallstones, kidney stones, severe vomiting, and diarrhea.
- Injuries and Trauma: Fractures, sprains, deep cuts requiring stitches, burns, head injuries, concussions, and injuries from motor vehicle or work-related accidents.
- Neurological Symptoms: Sudden severe headaches or migraines, stroke symptoms (weakness, numbness, slurred speech), seizures, and dizziness.
- Infections: Flu, UTIs, skin infections (cellulitis, abscesses), high fevers, and sepsis.
- Pediatric Emergencies: Specialized care for all minor and major childhood emergencies, including dehydration, croup, and febrile seizures.
- Allergic Reactions: Hives, swelling, and life-threatening anaphylaxis.
- Other Acute Conditions: Dehydration, diabetic emergencies, uncontrolled bleeding, poisoning, eye injuries, and more.
Why Choose SignatureCare Emergency Center?
We are accredited, open 24 hours and highly rated by our patients. Our physicians are experienced, and we are committed to providing an experience that reduces the stress of visiting an emergency room.
- Accredited for Quality: Our facility is accredited by The Joint Commission, reflecting our commitment to the highest standards of safety and quality care.
- Private Treatment Rooms: Every patient is seen in a private, comfortable room.
- Highly Rated Care: We are proud of our 5-star satisfaction ratings from hundreds of patients who praise our attentive, personable, and efficient care.
- Seamless Transfers: Should hospital admission be necessary, we provide ambulance service and coordinate a smooth transition to an area hospital.
- Streamlined Billing: We accept most insurance plans*, including Workers’ Compensation, and strive to make the billing process as clear and simple as possible.
Visit Us for Immediate Emergency Care
When you need an emergency room in Frisco, TX with experienced physicians, minimal wait times, and a family-friendly environment equipped with advanced technology, visit SignatureCare Emergency Center. Your health is our number one priority.
Questions or Career Inquiries? If you have non-emergency questions, please contact us. To apply for available positions at our Frisco emergency room, please visit our careers page.
Are you wondering if we accept your insurance plan? Please call our facility for billing information regarding your insurance coverage.
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Our emergency center has received The Joint Commission Gold Seal of Approval® and is officially Joint Commission Certified. We are also recognized as an Accredited Free-Standing Emergency Center by the Center for Improvement in Healthcare Quality (CIHQ), a nationally recognized accreditation provider.
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Inside SignatureCare Emergency Center - Frisco, TX 75035



