Now administering Regen-COV Monoclonal Antibody infusion treatment. Patients MUST be pre-screened for eligibility before coming to our ER. To get pre-screened, please call 1-888-871-6130. Go to our Monoclonal Antibody infusion page for more information.

Read our message to all patients.

THIS IS NOT A TESTING CENTER. While we have the ability to test patients for COVID-19, if you are not currently experiencing an emergency (i.e. shortness of breath, chest pain, etc.), you may wish to consider visiting a testing center instead. To locate a testing center, dial 2-1-1 on your phone and select Option 6 or visit Learn more about SignatureCare billing here. DO NOT sign-up for any appointments using the link below if you are not experiencing an emergency. Appointments are not necessary. We are ready to see you NOW! Because we are an emergency room, wait times are often unpredictable. Please do not sign-up for these reasons: Job clearance, travel clearance, day-care clearance, or “re-test” to see if you are negative now after testing positive earlier. Looking for your SignatureCare COVID-19 test results? Get more information here.
Although appointments are not necessary, for medical evaluation for COVID-19 only, please get an emergency room appointment here. Visit Katy Freeway or Memorial Drive Urgent Care if you suspect you have or may have been exposed to coronavirus (COVID-19). If you are looking for a free or low-cost COVID-19 testing center near you, visit the Texas COVID-19 Portal for more information.

Top-Rated Freestanding 24-Hour Emergency Room (ER) 

24-Hour Emergency Room, ER Near Me at SignatureCare Emergency Center in Texas

Due to Increased Volume, Wait Times May Be Longer in Our Emergency Rooms

At SignatureCare Emergency Center, Your Care is Our Signature

Each SignatureCare Emergency Center 24-hour emergency room is staffed with board-certified emergency physicians, licensed nurses, and trained support staff. Our ER services include a Full Lab, CT Scan, and X-rays. Each 24-hour emergency center is equipped to treat most major and minor medical emergencies for adults and children/pediatrics.

Looking for 24-hour ER Near you? Come into SignatureCare Emergency Center today!

This is a freestanding emergency medical care facility. When a patient receives an emergency evaluation at this facility, there is an associated facility fee and a physician fee charged for the medical care provided to the patient in addition to any testing and other services provided. Cost of COVID-19 tests are – 87635 (COVID Antibody, NAA) $175.00; 86769 (COVID PCR Antibody) $175.00; 87426 (COVID Antigen) $175.00; 87428 (SARS plus FLU A and B) $300.00 and 87633 (Respiratory Viral Panel) $834.00

How SignatureCare Emergency Center Protects You from COVID-19

During this COVID-19 pandemic, SignatureCare Emergency Center takes extra steps to keep the community safe when they visit our ER. Everyone including our staff, patients, and their family members wears masks while in the facility. We also enforce hand hygiene for everyone. All our facilities are equipped with HEPA air filtration, every room and furniture is sanitized before patients enter the rooms, all linens are changed for every new patient, and we have a negative pressure isolation room available should one be needed. At SignatureCare Emergency Center, we go beyond the minimum standard required for the safety of our patients and staff. We do COVID-19 antigen, antibody and molecular (PCR) evaluation.

Learn everything you need to know about coronavirus or get a CDC coronavirus self-checker.

SignatureCare Emergency Room (ER) Locations

Houston-Memorial City

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1014 Wirt Rd.
Houston, TX 77055
Tel: 832-834-6414


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3209 Montrose Blvd.
Houston, TX 77006
Tel: 281- 479-3293


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11103 Westheimer Rd.
Houston, TX 77042
Tel: 832-708-3651


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1925 E. TC Jester Blvd.
Houston, TX 77008
Tel: 832-742-0072


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5835 Hwy. 6 North
Houston TX 77084
Tel: 281-861-0937


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5413 South Rice Avenue
Houston, TX 77081
Tel: 713-669-9900

Houston-Cypress/FM 1960

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5003 Cypress Creek Pkwy
Houston, TX 77069
Tel: 281-213-5444

Mission Bend-Sugar Land

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8910 Hwy. 6 South
Houston, TX 77083
Tel: 281-258-4351


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3531 Main Street
Stafford, TX 77477
Tel: 281-410-2009


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2001 Mall Drive
Texarkana, TX 75503
Tel: 903-306-2126


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2731 N. Grandview Ave.
Odessa, TX 79762
Tel: 432-366-0945


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3055 NE Loop 286
Paris, TX 75460
Tel: 903-739-2116

 College Station/Bryan

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1512 Texas Ave. S, Ste 500
College Station, TX 77840
Tel: 979- 213-5728


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5701 W. Slaughter Ln, G101
Austin, TX 78749
Tel: 512-651-5787


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800 W. Central TX Expy
Killeen, TX 76541
Tel: 254-220-4117


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5409 West Wadley Ave.
Midland, TX 79707
Tel: 432-699-2601


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1596 W Main St.
Lewisville, TX 75067
Tel: 972-829-4862



21315 TX-130 Bldg. 4
Pflugerville, TX 78660
Tel: 512-354-4134



5324 Atascocita Road, Suite T Humble, TX 77346
Tel: 281-213-5063



3670 Hwy 121
Plano, TX 75025
Tel: 972-829-4866



621 Rayford Road
Spring, TX 77386
Tel: 281-973-0122

24-Hour Emergency Care

When you need emergency medical care, our ER doctors are available 24 hours to take care of you. SignatureCare Emergency Center treats most minor and major medical emergencies. Looking for an ER near you? SignatureCare has ER locations throughout Texas.

24-Hour Emergency Room. No Appointment Necessary. Walk-ins Always Welcome

Are you looking for a 24-hour ER near you? You will find one of our emergency centers nearby when you search for 24-hour ER near me in Texas. SignatureCare Emergency Centers’ 24-hour ERs are near you in Houston and other Texas cities. Our freestanding ER is fully equipped to meet your family’s emergency medical needs. Patients are seen by licensed physicians and trained registered nurses.

Our emergency centers are equipped to treat a wide range of medical emergencies. We function as your local hospital ER, without the wait.

Our 24-hour ER and walk-in clinic provides emergency care for most immediate medical care needs for adults and children. We have convenient emergency center locations throughout Texas including nine in the Houston area. See our emergency rooms in Houston, TX.

SignatureCare Emergency Center 24-Hour Freestanding ER

Fastest Growing 24-Hour ER Near You in Texas

We are the fastest growing ER in Texas, and there is an ER near you. We offer 24-hour emergency care services in our state-of-the-art freestanding emergency rooms including lab work,  X-ray, and CT scan.  Each emergency center is equipped to treat most minor or major medical emergencies.

Search for ER near me today to find the nearest ER to you! If your treatment requires overnight observation – our freestanding emergency centers have state-of-the-art observation rooms and highly trained medical staff. Our ER doctors are available on site 24 hours. This will assure you have the best medical care.

There is a SignatureCare Emergency Room Near You

Visit a SignatureCare Emergency Center ER near you today.  We treat children, infants and adults, and bill most insurance plans. We also see self-pay patients and you will always receive a free medical evaluation prior to any treatment. We treat dental emergencies when your dentist is closed and also provide emergency HIV – STD testing and treatment, based on the physician’s determination and diagnosis.

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