SignatureCare Emergency Center 281-258-4351

SignatureCare Emergency Room – Houston, TX

Read Our Message To All Patients.

THIS IS NOT A TESTING CENTER. While we have the ability to test patients for COVID-19, if you are not currently experiencing an emergency (i.e. shortness of breath, chest pain, etc.), you may wish to consider visiting a testing center instead. To locate a testing center, dial 2-1-1 on your phone and select Option 6 or visit Learn more about SignatureCare billing here. DO NOT sign-up for any appointments using the link below if you are not experiencing an emergency. Give those folks that are sick the opportunity to sign-up. You can always come in to our emergency room to get evaluated on-site without a registration fee, however you may have to wait at the ER. Because we are an emergency room, wait-times are often unpredictable.
Please do not sign-up for these reasons: Job clearance, Travel clearance, Day-care clearance, “re-test” to see if you are negative now after testing positive once.

Experiencing an emergency and need to be evaluated for COVID-19?
Get ER COVID-19 evaluation appointment

Suspect you have or may have been exposed to coronavirus (COVID-19)?
Click to visit Urgent Care Center

Interested in locating a free or low-cost testing center?
Go to Texas COVID-19 Portal

Looking for your SignatureCare COVID-19 test results? Get more information here.

24-Hour Emergency Room, SignatureCare Emergency Center Houston, TX

Top Rated Freestanding 24-Hour Emergency Room (ER)

10 Mins. or Less Wait-Time

At SignatureCare ER, Your Care is Our Signature

Each 24-hour emergency room is staffed with board-certified physicians, licensed nurses and trained support staff. Wait times are 10 minutes or less. Our ER services include a Full Lab, CT Scan and X-rays, and each emergency center is equipped to treat major and minor medical emergencies for adults and children/pediatrics.

This is a freestanding emergency medical care facility. When a patient receives an emergency evaluation at this facility, there is an associated facility fee and a physician fee charged for the medical care provided to the patient in addition to any testing and other services provided. Cost of COVID-19 tests are – 87635 (COVID Antibody, NAA) $175.00; 86769 (COVID PCR Antibody) $175.00 and 87426 (COVID Antigen) $175.00

How SignatureCare Emergency Center Protects You from COVID-19

During this COVID-19 pandemic, SignatureCare Emergency Center takes extra steps to keep the community safe when they visit our ER. Everyone including our staff, patients and their family members wear masks while in the facility. We also enforce hand hygiene for everyone. All our facilities are equipped with HEPA air filtration, every room and furniture is sanitized before patients enter the rooms, all linens are changed for every new patient, and we have a negative pressure isolation room available should one be needed. At SignatureCare Emergency Center, we go beyond the minimum standard required for the safety of our patients and staff. We do COVID-19 and antibody evaluation.

Coronavirus - COVID-19 Information
CDC Coronavirus COVID19 Self Checker

SignatureCare Emergency Room (ER) Locations

Houston-Memorial City

1014 Wirt Rd.
Houston, TX 77055
Tel: 832-834-6414


1007 Westheimer Rd.
Houston, TX 77006
Tel: 281- 479-3293


11103 Westheimer Rd.
Houston, TX 77042
Tel: 832-708-3651


1925 E. TC Jester Blvd.
Houston, TX 77008
Tel: 832-742-0072


5835 Hwy. 6 North
Houston TX 77084
Tel: 281-861-0937


5413 South Rice Avenue
Houston, TX 77081
Tel: 713-669-9900

Houston-Cypress/FM 1960

5003 Cypress Creek Pkwy
Houston, TX 77069
Tel: 281-213-5444

Mission Bend-Sugar Land

8910 Hwy. 6 South
Houston, TX 77083
Tel: 281-258-4351


3531 Main Street
Stafford, TX 77477
Tel: 281-410-2009


2001 Mall Drive
Texarkana, TX 75503
Tel: 903-306-2126


2731 N. Grandview Ave.
Odessa, TX 79762
Tel: 432-366-0945


3055 NE Loop 286
Paris, TX 75460
Tel: 903-739-2116

 College Station/Bryan

1512 Texas Ave. S, Ste 500
College Station, TX 77840
Tel: 979- 213-5728


5701 W. Slaughter Ln, G101
Austin, TX 78749
Tel: 512-651-5787


800 W. Central TX Expy
Killeen, TX 76541
Tel: 254-220-4117


5409 West Wadley Ave.
Midland, TX 79707
Tel: 432-699-2601


1596 W Main St.
Lewisville, TX 75067
Tel: 972-829-4862


21315 TX-130 Bldg. 4
Pflugerville, TX 78660
Tel: 512-354-4134


5324 Atascocita Road, Suite T Humble, TX 77346
Tel: 281-213-5063

Dripping Springs

333 East Highway 290 #350
Dripping Springs, TX 78620
Tel: 512-436-0929

24-Hour Emergency Care

When you need emergency medical care, our ER doctors are available 24 hours to take care of you. We treat you like family. SignatureCare Emergency Center treats most minor and major emergencies, and wait times are typically 10 minutes or less.

Houston, TX Emergency Room, SignatureCare Emergency Center

Freestanding 24-Hour Emergency Room Near You!

10 Minutes or Less Wait for ER Physician.

SignatureCare Emergency Centers’ 24-hour emergency rooms are located near your home in Houston and other Texas cities. Our freestanding emergency room (ER) is fully equipped to meet all your family’s emergency medical needs. Patients are seen in 10 minutes or less by licensed physicians and trained emergency room registered nurses.

Our emergency rooms are equipped to treat a wide range of medical emergencies. We function like your local hospital ER, without the wait.

Average wait time to see a medical doctor in our emergency clinic is 10 minutes or less. Our 24-hour ER provides emergency treatment for most immediate medical care needs for adults and children. We have convenient emergency room locations throughout Texas including nine in the Houston area. See our emergency rooms in Houston, TX.

Fastest Growing 24-Hour ER in Texas

We are the fastest growing emergency centers in Texas and we offer 24-hour emergency care services including lab work,  X-ray and CT scan.  Each ER is equipped to treat most minor or major medical emergencies.

If your treatment requires overnight observation – our freestanding emergency centers have state-of-the-art observation rooms and highly trained medical staff. Our ER doctors are available on site 24 hours. This will assure you have the best medical care.

There is an Emergency Room near you

Visit a SignatureCare Emergency Center ER near you today.  We treat children, infants and adults, and bill most insurance plans. We also see self – pay patients and you will always receive a free medical evaluation prior to any treatment. We treat dental emergencies when your dentist is closed and also provide emergency HIV – STD testing and treatment, based on physician’s determination and diagnosis.

SignatureCare Emergency Center- “Your Care is Our Signature”

SignatureCare Emergency Center News and Videos

TCU Medical Student Wins SignatureCare Emergency Center’s 2020 Fall Scholarship Award –

Sereena Jivraj, 2020 fall semester scholarship award winnerSereena Jivraj, a freshman medical student at Texas Christian University (TCU) and the University of North Texas Health Science Center (UNTHSC), has been awarded SignatureCare Emergency Center’s 2020 fall semester Medical and Health Scholarship for her passion and commitment to the medical field.

Online COVID-19 Evaluation Appointment Portal for ER Patients –

SignatureCare Emergency Center COVID-19 Evaluation PortalIn an effort to ease the long wait in the emergency room to get coronavirus evaluation, SignatureCare Emergency Center has created a COVID-19 evaluation portal that allows patients to easily set up appointments online and get their COVID-19 evaluation done at their convenience.

SignatureCare Emergency Center Offering Rapid COVID-19 Tests at 18 ER Locations –

SignatureCare Emergency Center, Copperfield, Houston, TXWorried that you may have been exposed to COVID-19 and need to be evaluated? SignatureCare Emergency Center now allows patients who believe they may have been exposed to COVID-19 to get the needed evaluation at any SignatureCare Emergency Center’s 24-hour emergency rooms in Texas.

SignatureCare Emergency Center Achieves Medicare Certification –

SignatureCare Emergency CenterAll SignatureCare Emergency Center emergency room locations except South Austin and Pflugerville are now certified to treat all Medicare and Medicare Advantage participants, and Killeen, College Station/Bryan, Midland, Odessa, Paris, and Copperfield (Northwest Houston area), TX are accredited to bill active military insurance plans. South Austin and Pflugerville are in the process of being Medicare certified. Get more details here.

SignatureCare Emergency Center Expands to Pflugerville, TX –

Pflugerville Emergency CenterSignatureCare Emergency Center, your friendly neighborhood 24-hour Texas emergency room is expanding to the Austin suburb of Pflugerville, TX. The new emergency center will serve residents of Pflugerville, Hutto, Round Rock, San Marcos and other nearby Texas cities. It is set to open early June, 2020, and will be located on the southeast corner of SH 130 and Gattis School Road at 21315 N SH 130, Bldg.4, Pflugerville, TX.

SignatureCare Emergency Center Salutes All Nurses on National Nurses Week 2020 –

Emergency Room NursesAt SignatureCare Emergency Center, we celebrate Emergency Nurses Week, and will like to extend our thanks to all nurses this National Nurses Week 2020. From the Senior Leadership team, THANK YOU for all you do and for giving our patients exceptional care. We appreciate all of you! See all the freebies for nurses here.
We are hiring for our new ER in Pflugerville, TX

For our videos and more news stories, please go to our News and Videos page. Learn everything you need to know about coronavirus (COVID-19).